What’s next in the effort to squelch the illegal drug trade?

It was an inglorious end for the legendary drug lord, Joaquin "El Chapo" Guzman. He was perp-walked before cameras in Mexico City over the weekend and marched off to jail. His capture, in an apartment in the western resort city of Mazatlan early Saturday morning, was the dramatic end of a 13-year manhunt, a search that intensified in the last two weeks.

Guzman was capture by Mexican marines with the help of American agents and tracking technology. In the end, it was an intercepted satellite phone call that did him in. He was asleep in his room with an AK-47 by his side, but no shots were fired. "El Chapo," or "Shorty," is the world's most wanted drug lord. The mastermind behind a criminal drug production and smuggling enterprise measured in billions of dollars. It moved tons of cocaine, marijuana and other illegal drugs over the border and onto U.S. streets as well as other nations’.

People in Mexico are breathing a sigh of relief. Francisco Alcocer, a resident of Mexico City, said, "It's an excellent achievement from this government, who are giving us results." He said Guzman's arrest is good news not just for Mexico but also "for many countries, it's an important arrest."

Guzman's Sinaloa drug cartel is one of the most violent in Mexico, known for its ruthless tactics toward competing cartels and using tunnels to sneak tons of drugs under the U.S. border. The capture of "El Chapo" could have a major impact on illegal drug supplies around the world.

At a press conference held on the airfield that ushered Guzman to prison, Mexico's Attorney General Jesus Murillo Karam said the arrest was not easy. "Several homes that he used were discovered, and in some of those homes, which is what complicated the arrest, we discovered that it was connected by several tunnels to seven homes — not only connected by several tunnels, but he always used the city's drainage system."

Guzman's elusiveness is legendary. This is not the first time he's been caught. After he was sentenced to 20 years in prison back in 1993, his legend grew when he escaped a high-security prison in 2001. With the help of millions of dollars in bribes, he escaped by hiding in a laundry van.

The arrest is seen as a political triumph for Mexican President Enrique Peña Nieto, who took office in 2012. Behind the capture of "El Chapo" and the larger efforts against Mexican cartels is a security cooperation agreement between the U.S. and Mexico called the Merida Initiative.

A $1.6 billion aid program that started in 2008, it reinforced the Mexican military's hardware in the initiatives' early days and today focuses on training police, prosecutors and others to prevent drug violence.

Still, nearly 100,000 Mexicans are estimated to have been killed, caught in the violence of an ongoing war between Mexican law enforcement and the drug gangs. In recent years, many top syndicate members have been arrested or killed.

U.S. Attorney General Eric Holder said El Chapo's alleged criminal activities "contributed to the death and destruction of millions of lives across the globe through drug addiction, violence and corruption."

The United States had a $5 million bounty on Guzman's head. The government is seeking his extradition for crimes he allegedly committed in the U.S.

He faces a variety of drug and money-laundering charges in New York, Illinois, Florida and Texas. Mexico's attorney general has not commented on the possibility of extradition. Meanwhile, though the reputed head of the Sinaloa cartel is behind bars tonight, the organization is not out of business. And it is not the only cartel operating in Mexico to supply Americans' enormous appetite for drugs.